In 1914, the Big Ten Conference endowed a Medal of Honor, to be awarded annually at each institution, to a student in the graduating class that has demonstrated proficiency in scholarship and athletics. Winners in 1964 were 50th Anniversary winners of the Medal of Honor. Beginning in 1982, a senior woman athlete from each institution has been awarded the Conference Medal of Honor.

| Year |
Male Recipient |
Female Recipient |
| 2015 |
Varun Ram, Men's Basketball |
Malina Howard, Women's Basketball |
| 2016 |
Michael McCarney, Men's Lacrosse |
Rachelle Beanlands, Women's Soccer |
| 2017 |
Cody Niedermeier, Men's Soccer |
Zoe Stukenberg, Women's Lacrosse |
| 2018 |
Alex Leto, Track & Field |
Kristen Confroy, Women's Basketball |
| 2019 |
Jahi Jones, Wrestling |
Abigail Bentz, Volleyball |
| 2020 |
Jared Bernhardt, Men's Lacrosse |
Kaila Charles, Women's Basketball |
| 2021 |
Roman Puglise, Men's Lacrosse |
Grace Griffin, Women's Lacrosse |
| 2022 |
Logan Wisnauskas, Men's Lacrosse |
Brooke DeBerdine, Field Hockey |
| 2023 |
Nick Lorusso, Baseball |
Diamond Miller, Women's Basketball |
| 2024 |
Ajax Zappitelo, Men's Lacrosse |
Emily Sterling, Women's Lacrosse |
| 2025 |
Jaxon Smith, Wrestling |
Emma DeBerdine, Field Hockey |
| 2026 |
Will Schaller, Men's Lacrosse |
Kori Edmondson, Women's Lacrosse |